ISSN 1308-8734 | E-ISSN 1308-8742
1 Sütçü İmam University, Department of Physical Medicine and Rehabilitation, Kahramanmaraş, Turkey  
2 Sütçü İmam University, Faculty of Medicine, Department of Neurology, Kahramanmaraş, Turkey  
3 Sütçü İmam University, Faculty of Medicine, Department of Clinic Biochemistry, Kahramanmaraş, Turkey  
Eurasian J Med ; : -


Objective: Cardiovascular complications are still the primary reason for high mortality rates worldwide. The determination of risk factors is important to prevent stroke. This study analyzed the importance of serum lipid indexes and urinary sodium (Na)/potassium (K) excretion in patients with stroke together with sex differences.


Method: A total of 50 patients with acute stroke were included in the study group (28 males and 22 females, with a mean age of 65.9±14.6 years), and 32 body mass index-matched healthy subjects were included as the control group. Lipid profiles [cholesterol (c), triglyceride (TG), very-low-density lipoprotein (VLDL), low-density lipoprotein (LDL), and high-density lipoprotein (HDL)], serum creatinine (Cre), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and Na, K, and Cre excretion in spot urine samples of the patients were recorded.


Results: Systolic blood pressure (P = .021), ESR (P = .044), and CRP (P= .042) were significantly higher in all patients in the stroke group; urinary Tanaka (K) (P = .033), Kawazaki (K) (P = .028), urinary spot Cre (P = .012), and sodium (Na) excretion (P= .036) were found to be significantly lower in only the male patients with stroke. The mean plasma atherogenic index (PAI) was 0.57±.24 in the study (stroke) group and 0.54±0.22 in the control group (P= 0.61). Other lipid indexes such as Castelli’s Risk Index (CRI)-I (P=.29), CRI-II (P=.24), atherogenic coefficient (AC) (P=.29), and non-HDL cholesterol (NHC) (P=.69) werenot statistically different from the controls.


Conclusion: Urinary Na, K, and Cre excretion were significantly lower in male patients with stroke, and acute-phase reactants were significantly higher in the entire stroke group than in the controls. These parameters can be used as auxiliary biomarkers in the risk assessment of stroke. 


You may cite this article as: Koca TT, Tugan CB, Seyithanoğlu M, Koçyiğit BF. The Clinical Importance of the Plasma Atherogenic Index, Other Lipid Indexes, and Urinary Sodium, and Potassium Excretion in Patients with Stroke. Eurasian J Med 2019; DOI: 10.5152/eurasianjmed.2019.18350.

Key Words
Author’s Corner
AVES | Copyright © 2019 Atatürk University Faculty of Medicine | Latest Update: 14.06.2019