ISSN 1308-8734 | E-ISSN 1308-8742
Original Article
Is Adenoidectomy and/or Tonsillectomy a Risk Factor for Allergic Diseases and Asthma in Adulthood?
1 Division of Allergy and Immunology, Department of Chest Diseases, Ankara University School of Medicine, Ankara, Turkey  
2 Department of Biostatistics, Ankara University School of Medicine  
Eurasian J Med ; : -
DOI: 10.5152/eurasianjmed.2018.17182
Key Words: Asthma, chest diseases, pulmonology, allergy, dermatology, immunology, internal medicine
Abstract

Objective: To investigate the relationship between adenoidectomy and/or tonsillectomy in childhood and allergic diseases in adulthood. 


Materials and Methods
: A case-control study of 510 patients (F/M: 379/131) who were followed by our department between January-June 2014 with diagnosis of asthma (248), allergic rhinitis (205), urticaria-angioedema (73), drug allergy (82), food allergy (24) and venom allergy (14) and agreed to participate in the study was conducted using a survey and clinical data. 65 (%12.7) of these patients had adenoidectomy and/or tonsillectomy. Out of 65 patients; 41 had asthma, 33 had allergic rhinitis and 28 had other allergic diseases. Patients were evaluated as ''above 15 years of age'' and ''below 15 years of age'' 


Results
: No relation between history of atopy and adenoidectomy and/or tonsillectomy (p=0.129) was detected in both groups, however there was a positive relationship between asthma and patients under the age of 15 with history of tonsillectomy and/or adenoidectomy (p=0.200). The risk of asthma was determined to be increased by 1.96 fold among our patients if the patient had been adenoidectomized and/or tonsillectomized (CI:1.14-3.36). No connection was found between atopic and non-atopic asthmatic patients in relation to adenoidectomy and/or tonsillectomy (p=0.46). There was no relationship between allergic rhinitis and adenoidectomy and/or tonsillectomy.


Conclusion
: Adenoidectomy and/or tonsillectomy in childhood increases the risk of asthma in adulthood while it doesn't increase the risk of atopy. This results can signify the importance of adenoidectomy or tonsillectomy in the pathogenesis of asthma. 


Cite this article as
: Yurtsever N, Soyyigit S, Celebi Sozener Z, Mungan D, Kose SK, Misirligil Z. Is Adenoidectomy and/or Tonsillectomy a Risk Factor for Allergic Diseases and Asthma in Adulthood? Eurasian J Med 2018; 50: 10.5152/eurasianjmed.2018.17182

Key Words
Authors
All
Author’s Corner
Survey
AVES | Copyright © 2018 Atatürk University Faculty of Medicine | Latest Update: 20.07.2018