Abstract

In this study, we investigated the frequency of iodine-induced thyrotoxicosis in patients performed coronary angiography (CA) in the iodine deficiency regions. In the study and control group patients the thyroid volume, basal thyrotropin (TSH), free thyroxine (T4) and thyroid antibodies against thyroid peroxidase (TPO) were measured at different times. While one of 44 patients developed clinical hyperthyroidism, fifteen patients developed subclinical hyperthyroidism during the study period in study group. Subclinical hyperthyroidism was diagnosed in seven of 40 in control group. The subject showing iodine induced hyperthyroidism, and nine of fifteen patients having subclinical hyperthyroidism in the study belonged to the so-called risk group. Six of 15 patients with subclinical hyperthyroidism did not belong to risk group for iodine-induced thyrotoxicosis. This study showed that contrast media used during the coronary angiography could lead to iodine-induced thyrotoxicosis in patients with and without risk group. Therefore in patients receiving contrast media, especially in areas iodine-deficiency, TSH and thyroid hormone levels should be followed-up after coronary angiography.