Abstract
Thrombocytopenia is one of the most frequent haematological disorders in patients with chronic liver disease. We present a case of a 65-year-old woman who referred to our outpatient of haematology for chronic hepatitis B virus (HBV) infection and chronic Immune thrombocytopenic purpura (ITP). A sustained normalization of platelet count was observed during antiviral therapy without of administration corticosteroid or immunoglobulin.