The Eurasian Journal of Medicine

Sepsis: Immunopathology, Immunotherapies, and Future Perspectives


Ataturk University, Faculty of Medicine, Department of Pharmacology, Erzurum, Turkey

Eurasian J Med 2022; 54: Supplement S127-S132
DOI: 10.5152/eurasianjmed.2022.22314
Read: 715 Downloads: 334 Published: 01 December 2022

Sepsis is a syndrome that includes physiological, pathological, and biochemical abnormalities resulting from the host immune response to infection. Despite the improved treatment modalities in recent years, the incidence and mortality of sepsis are still increasing. Sepsis immunopathology is increasingly attracting the attention of researchers. The successes experienced with immunotherapeutics in the treatment of cancer and coronavirus disease 2019, which are diseases with similar pathophysiological features and common immune defects with sepsis, have given rise to the hope that similar successes can be achieved in the treatment of sepsis. In this review, future perspectives on the immunopathology of sepsis and immunotherapeutics are presented to improve the current understanding of the disease.

Cite this article as: Tavaci T, Akgun N. Sepsis: Immunopathology, immunotherapies, and future perspectives. Eurasian J Med., 2022;54(Suppl. 1):S127-S132

EISSN 1308-8742