ISSN 1308-8734 | E-ISSN 1308-8742
Regulatory Peptide: Nesfatin-1 and Its Relationship with Metabolic Syndrome
1 Department of Nutrition and Dietetics, Sivas Cumhuriyet University School of Health Sciences, Sivas, Turkey  
2 Department of Nutrition and Dietetics, Erciyes University School of Health Sciences, Kayseri, Turkey  
Eurasian J Med ; : -
DOI: 10.5152/eurasianjmed.2019.18420
Key Words: Metabolic syndrome, Nesfatin-1, obesity, peptide


Metabolic syndrome is associated with a group of conditions abdominal obesity, high triglyceride levels, reduction in low-density lipoprotein, increased blood pressure, and increased fasting blood glucose. Hence, it poses a risk for type 2 diabetes and cardiovascular diseases. The prevalence of metabolic syndrome increases with age. Nesfatin-1, which affects different systems, has recently been discovered as a regulatory peptide molecule. With the discovery of nesfatin-1, it has been reported to inhibit the intake of nutrients and have significant regulatory effects on energy metabolism. As nesfatin-1 is present in both central and peripheral tissues, it is thought to have many functions. In addition to its suppressive effect on food intake, nesfatin-1 has also been reported to have an effect on the blood glucose level for regulating cardiac functions and affecting obesity by providing weight loss. Considering the effects of nesfatin-1, it may be associated with metabolic syndrome.


Cite this article as: Tekin T, Çiçek B, Konyalıgil N. Regulatory Peptide Nesfatin-1 and its Relationship with Metabolic Syndrome. Eurasian J Med 2019; DOI: 10.5152/eurasianjmed.2019.18420.

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