ISSN 1308-8734 | E-ISSN 1308-8742
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A Regulatory Peptide: Nesfatin-1 and Its Relationship with Metabolic Syndrome
1 Department of Nutrition and Dietetics, Sivas Cumhuriyet University, Faculty of Health Sciences, Sivas, Turkey  
Eurasian J Med ; : -
DOI: 10.5152/eurasianjmed.2019.18420
Key Words: Metabolic Syndrome, Nesfatin-1, Obesity, Peptide
Abstract

Abdominal obesity, high triglyceride levels, decline in low-density lipoprotein, increased blood pressure and increased fasting blood glucose are the components of metabolic syndrome. As it includes these components, the metabolic syndrome poses a risk for type 2 diabetes and cardiovascular diseases. The prevalence of metabolic syndrome is increasing with age. Nesfatin-1, which has effects on different systems, has recently been discovered as a regulatory peptide molecule. With the first discovery of Nesfatin-1, it has been reported to inhibit the intake of nutrients and to have significant regulatory effects on energy metabolism. Nesfatin-1 is present in both central and peripheral tissues. It is thought to have many functions due to its presence in both central and peripheral tissues. In addition to its suppressive effect on food intake, nesfatin-1 has also been reported to have an effect on the blood glucose level, to regulate cardiological functions and to have effects on obesity by providing weight loss. Considering the effects of nesfatin-1, it may be associated with metabolic syndrome.

 

You may cite this article as: Tekin T, Çiçek B, Konyalıgil N. A Regulatory Peptide: Nesfatin-1 and Its Relationship with Metabolic Syndrome. Eurasian J Med 2019; DOI: 10.5152/eurasianjmed.2019.18420.

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