Abstract

Introduction: Brain natriuretic peptide (BNP) is a highly sensitive and specific diagnostic tool used in prediction of cardiovascular events in patients with ischemic and non-ischemic cardiovascular heart disease. In this study, we sought to test the efficacy of BNP in predicting restenosis rate in patients who had undergone PCI.

Materials and Methods: Seventy-three consecutive stable angina and acute coronary syndrome patients who were admitted to cardiology department and performed percutaneous coronary intervention (PCI) were included in this study. The study was performed in Duzce University School of Medicine, Dept of Cardiology between 2006 and 2008. Pre and post PCI BNP levels were measured in all the patients. The patients were followed up for stent restenosis.

Results: Sixteen out of 23 patients who were screened for restenosis with coronary angiography were found to have restenosis. The differences between the mean BNP levels measured before and after PCI were not statistically significant.

Conclusion: BNP measured before and after PCI could not predict restenosis.