Mean Platelet Volume, Neutrophil-To-Lymphocyte Ratio, and Platelet-To-Lymphocyte Ratio as İnflammatory Markers in patients with Recurrent Aphthous Stomatitis

Objective: The aim of this study is to examine the associations between white blood cell (WBC), hemoglobin (Hb), neutrophil, lymphocyte, platelet, mean platelet volume (MPV), the neutrophil-to-lymphocyte ratio (NLR) , platelet-to-lymphocyte ratio (PLR), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) in patients with recurrent aphthous stomatitis (RAS).

Materials and Methods: One hundred and thirty-seven (137) patients with RAS and 137 healthy controls were recruited. The study participants had no systemic diseases except RAS. The serum WBC, Hb, neutrophil, lymphocyte, platelet, MPV, PLR, NLR ,ESR and CRP, levels were recorded all patients with RAS in the active period and controls.

Results: There was no statistically significant difference in the WBC, Hb, neutrophil, lymphocyte, platelet, MPV, NLR PLR, ESR and CRP levels between patients with RAS and controls.

Conclusion: WBC, Hb, neutrophil, lymphocyte, platelet, MPV, NLR, PLR, ESR and CRP levels did not differ in patients with RAS patients. These parameters cannot be used as a marker- of inflammation and inflammation severity in patients with RAS.

Cite this article as: Cakmak Karaer I. Mean Platelet Volume, Neutrophil-To-Lymphocyte Ratio, and Platelet-To-Lymphocyte Ratio as Inflammatory Markers in patients with Recurrent Aphthous Stomatitis. Eurasian J Med 2020; 52(1): 38-40.